1.指南来源（Guide Source）:

NCCN临床实践指南:肝细胞癌 V2.2025.发布已获NCCN肿瘤学临床实践指南(NCCN指南®)许可。©2025美国国家综合癌症网络公司.保留所有权利。未经NCCN明确的书面许可，不得出于任何目的以任何形式复制NCCN指南®和文中的插图。要查看NCCN指南的最新完整版本，请访问NCCN.org。NCCN指南是一项持续进行的工作，可能会随着新的重要数据的出现而不断完善。 

2.免责声明（Disclaimers）：

NCCN对其内容、使用或应用不做任何形式的担保，并否认以任何方式对其应用或使用承担任何责任。

在下载本篇指南前，请先您详细阅读并同意以下协议：

NCCN内容不得用于商业目的，以及NCCN作为NCCN内容的许可方，不作任何陈述或保证，并明确否认NCCN指南适用于任何特定患者的护理或治疗，任何医院、寻求使用《NCCN指南》治疗患者的临床医生或其他医疗服务提供者(“提供者”)应根据特定患者护理或治疗的具体临床情况做出独立的医疗判断，NCCN不建议、推荐或认可任何提供者(无论是否与被许可方相关)进行任何有偿或无偿的医疗治疗、咨询或服务，也不应因被许可方建议、推荐或认可任何此类提供者的作为或不作为而直接或间接承担责任。详见《NCCN最终用户许可协议》

3.专家名单（Staff）：

*Al B. Benson, III, MD/Chair † Robert H. Lurie Comprehensive Cancer Center of Northwestern University

*Michael I. D’Angelica, MD/Vice-Chair ¶ Memorial Sloan Kettering Cancer Center

Thomas Abrams, MD † Dana-Farber/Brigham and Women's Cancer Center | Massachusetts General Hospital Cancer Center

Daniel E. Abbott, MD ¶ University of Wisconsin Carbone Cancer Center

Aijaz Ahmed, MD ¤ Stanford Cancer Institute

Daniel A. Anaya, MD ¶ Moffitt Cancer Center

Robert Anders, MD, PhD ¤ ≠ The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Chandrakanth Are, MD, MBA ¶ Fred & Pamela Buffett Cancer Center

Melinda Bachini ¥ The Cholangiocarcinoma Foundation

David Binder, MD § University of Colorado Cancer Center

Mitesh Borad, MD † Mayo Clinic Comprehensive Cancer Center

Christopher Bowlus, MD ¤ UC Davis Comprehensive Cancer Center

Daniel Brown, MD † ф Vanderbilt-Ingram Cancer Center

Adam Burgoyne, MD, PhD † US San Diego Moores Cancer Center

Prabhleen Chahal, MD ¤ Case Comprehensive Cancer Center/ University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute

Jordan Cloyd, MD ¶ The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute

Anne M. Covey, MD ф Memorial Sloan Kettering Cancer Center

Evan S. Glazer, MD, PhD ¶ St. Jude Children's Research Hospital/The University of Tennessee Health Science Center

William G. Hawkins, MD ¶ Siteman Cancer Center at Barnes- Jewish Hospital and Washington University School of Medicine

Renuka Iyer, MD Þ † Roswell Park Comprehensive Cancer Center

Rojymon Jacob, MD § O'Neal Comprehensive Cancer Center at UAB

Lawrence Jennings, MD, PhD ≠ Robert H. Lurie Comprehensive Cancer Center of Northwestern University

R. Kate Kelley, MD † ‡ UCSF Helen Diller Family Comprehensive Cancer Center

Robin Kim, MD ξ ¶ Huntsman Cancer Institute at the University of Utah

Matthew Levine, MD, PhD ξ Abramson Cancer Center at the University of Pennsylvania

Manisha Palta, MD § Duke Cancer Institute

James O. Park, MD ¶ Fred Hutchinson Cancer Center

Steven Raman, MD ф UCLA Jonsson Comprehensive Cancer Center

Sanjay Reddy, MD, FACS ¶ Fox Chase Cancer Center

Vaibhav Sahai, MBBS, MS † University of Michigan Rogel Cancer Center

Gagandeep Singh, MD ¶ City of Hope National Medical Center

Stacey Stein, MD † Yale Cancer Center/Smilow Cancer Hospital

Anita Turk, MD † Indiana University Melvin and Bren Simon Comprehensive Cancer Center

Jean-Nicolas Vauthey, MD ¶ The University of Texas MD Anderson Cancer Center

Alan P. Venook, MD † ‡ Þ UCSF Helen Diller Family Comprehensive Cancer Center

Adam Yopp, MD ¶ UT Southwestern Simmons Comprehensive Cancer Center  

4.临床试验（Clinical Trials）：

NCCN认为任何癌症患者都可以在临床试验中得到最佳治疗，因此特别鼓励患者参与临床试验。 寻找NCCN成员组：https://www.nccn.org/home/member-institutions

5.NCCN对证据和共识分类（ NCCN Categories of Evidence and Consensus）：

推荐均为2A类，除非另有说明，请参见下表： 

6.NCCN首选分类（ NCCN Categories of Preference）：

所有建议均视为合理，请参见下表：